General medicine case



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A 69 year old female was brought to the casuality with chief complaints of sudden onset of aphasia preceded by 2 episodes of vomiting and staring look 

History of present illness : 

She was apparently asymptomatic and coherent after then she had 2 episodes of vomiting and after which  she had difficulty in speech , generalised weakness , staring look at times ,difficulty in walking, walking with support  , patient was unable to recognize her family members. 

She had similar episodes of vomiting associated with weakness and disorientation 10 days back .  She became stable when she was given adequate food and fluids at home in 2 days . 

 Past history: 

No history of diabetes mellitus , hypertension , thyroid , epilepsy , seizures. 

No history of surgeries 

No history of fear , repetitive thought of action 

Personal history : 

Diet: mixed 

Non alcoholic

No smoking habits 

Appetite: decreased 

Sleep : decreased 

Family History: 

No similar history in the family 

Treatment history:

Not significant 

General examination:

30/9/2021:

Conscious (confused)

Intermittent coherence

Speech: response to few commands

2/10/2021:

Irrelevant talk intermittently

No fresh complaints

4/10/2021:

Irritability and irrelevant talk reduced

Patient is able to recognise family members at times and hallucinating behaviour decreased

Vitals:

30/10/2021:

BP: 120/60 mm Hg

PR: 84bpm

1/10/2021:

Temp: Afebrile

BP:110/60mm Hg

PR: 88 bpm

2/10/2021:

Temp: 97.5 F

BP: 120/60mm Hg

PR: 86 bpm (regular)

3/10/2021:

Temp 97.5 F

BP: 110/80mm Hg

PR : 88bpm regular

Systemic examination: 

1/10/2021: 

CVS: S1 S2 + no murmur

RESP System: Resonated breath sounds in B/L ISA

P/A - soft, no tenderness


2/10/2021:

CVS: S1S2 + No murmur

Rs: NVB1 decreased breath sounds in lt RSA

P/A soft, no tenderness

I/O 2200/1600 ml

GRBS 152 mg/dl


3/10/2021:

CVS: S1S2 + No  murmur

Rs: NVB1 decreased breath sounds in lt RSA

P/A soft, no tenderness

I/O 1550/1400 ml

GRBS 150mg/dl

Investigations : 

Complete blood picture : 


MRI : 


ECG : 


CBP , Serum electrolyte , LFT 


Other investigations: 





Medication history:


1/10/2021:
INJ.PAN 40mg i.v OD
INJ.ZOFER 16mg i.v SOS 
TAB. DOLO 650mg PO OD
INJ.OPTINEURO 650mg OD
INJ.MONOCEF 1g I.v OD

2/10/2021:
INJ. PAN 40mg I.v OD
INJ.ZOFER 4mg I.v SOS
TAB. DOLO 650mg PO SOS
SYP.ABROXY 10 mg PO TID
INJ.MONOCEF 1g I.v BD
TAB.ADMENTA 10mg PO OD
TAB.OLANZAPINE 5mg PO OD

3/10/2021:
INJ.PAN 40mg I.v OD
INJ.ZOFER 4mg I.v SOS
INJ.MONOCEF 1g I.v BD
INJ.DOLO 650mg PO SOS
SYP.AMBROXYL 10ml PO SOS
TAB.OLANZAPINE 5mg PO OD

4/10/2021:
INJ.PANTOP 40mg i.v OD
INJ.ZOFER 4mg i.v SOS
TAB.DOLO 650mg PO TID
SYP.AMBROXYL 10ml PO TID
INJ.MONOCEF 1g I.v BD
TAB.ADMENTA 10mg PO OD
TAB.OLANZAPINE 2.5mg PO OD
INJ.HALOPERIDOL 1/2amp/I.M/SOS(if patient is irritable)
INJ.LACTULOSE 15ml/PO/HS
IVF (NS and RL) 75ml/hr
1amp of OPTINEURON I.v OD

Provisional diagnosis: 

Wernickes Aphasia 

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